Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Pimelic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | FABP3 | P05413 | 9/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL2237813 | 1.00 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL10929213 | 1.00 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL28866667 | 1.00 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL11076790 | 1.00 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Azelaic Acid SCHEMBL8066498 | 1.00 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Adipic Acid SCHEMBL518167 | 0.96 | CA1 (0.58) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL11668419 | 0.93 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL8386996 | 0.93 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 | |
| SCHEMBL11046980 | 0.93 | CA1 (0.63) | CA1FABP3FFAR3HDAC3HDAC1 | |
| Octanedioate SCHEMBL7211261 | 0.93 | CA1 (0.55) | CA1FABP3FFAR3HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456287-B | Catalyst component and catalyst and method for homo-polymerization of ethylene or copolymerization of ethylene and alpha-olefin | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-114456285-B | Catalyst component and catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2023-08-15 | — | — | CN | claimed |
| CN-110600655-B | Biaxially oriented aliphatic polyketone microporous membrane and preparation method and application thereof | 广东工业大学 | 2022-11-04 | — | — | CN | claimed |
| CN-114456287-A | Catalyst component and catalyst and method for homopolymerization of ethylene or copolymerization of ethylene and alpha-olefin | 中国石油化工股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| CN-114456285-A | Catalyst component and catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2022-05-10 | — | — | CN | claimed |
| US-20240376295-A1 | TREATED INORGANIC PARTICLES FOR MODIFYING POLYMER CRYSTALLINITY | THE CHEMOURS COMPANY FC, LLC (US) | 2024-11-14 | — | — | US | disclosed |
| EP-4384578-A1 | TREATED INORGANIC PARTICLES FOR MODIFYING POLYMER CRYSTALLINITY | The Chemours Company FC, LLC (US) | 2024-06-19 | — | — | EP | disclosed |
| WO-2023018616-A1 | TREATED INORGANIC PARTICLES FOR MODIFYING POLYMER CRYSTALLINITY | THE CHEMOURS COMPANY FC, LLC (US) | 2023-02-16 | — | — | WO | disclosed |
| EP-3500238-B1 | COLOR PROTECTION HAIR TREATMENT AGENT WITH EARTH ALKALINE SALTS OF DICARBOXYLIC ACIDS | HENKEL AG & CO KGAA (DE) | 2022-12-07 | — | — | EP | disclosed |
| CN-110600655-B | Biaxially oriented aliphatic polyketone microporous membrane and preparation method and application thereof | 广东工业大学 | 2022-11-04 | — | — | CN | disclosed |
| CN-114456287-A | Catalyst component and catalyst and method for homopolymerization of ethylene or copolymerization of ethylene and alpha-olefin | 中国石油化工股份有限公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456285-A | Catalyst component and catalyst for olefin polymerization and olefin polymerization method | 中国石油化工股份有限公司 | 2022-05-10 | — | — | CN | disclosed |