SCHEMBL29624352

SCHEMBL29624352

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(N)=O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 14/20 0.57
NPY5R Q15761 9/20 0.57
NPY1R P25929 9/20 0.57
NPY2R P49146 6/20 0.57
QRFPR Q96P65 4/20 0.56
CTSL P07711 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30064048 0.96 NPY4R (0.59) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL31679035 0.95 NPY4R (0.55) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL29447211 0.94 GNPAT (0.54) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL30692729 0.94 GNPAT (0.54) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL5598751 0.91 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL5598748 0.91 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL29447208 0.91 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL4590047 0.90 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL2249230 0.90 NPY4R (0.52) NPY4RNPY5RNPY1RNPY2RQRFPR
SCHEMBL24713048 0.90 QRFPR (0.53) NPY4RNPY5RNPY1RNPY2RQRFPR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240309074-A1 ENGINEERED MICROBE-TARGETING MOLECULES AND USES THEREOF PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2024-09-19 US disclosed
US-11795212-B2 Engineered microbe-targeting molecules and uses thereof PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2023-10-24 US disclosed
US-20220195017-A1 PATHOGEN BINDING METHODS AND COMPOSITIONS PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2022-06-23 US disclosed