Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 20/20 | 0.55 |
| ▸ | EGFR | P00533 | 11/20 | 0.48 |
| ▸ | ERBB2 | P04626 | 11/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2958118 | 0.84 | IGF1R (0.64) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2963660 | 0.83 | IGF1R (0.60) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2953655 | 0.75 | IGF1R (0.71) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2962616 | 0.75 | IGF1R (0.71) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2953657 | 0.75 | IGF1R (0.71) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2957993 | 0.74 | IGF1R (0.62) | IGF1REGFRERBB2CYP2D6 | |
| SCHEMBL2956438 | 0.73 | IGF1R (0.60) | IGF1REGFRERBB2 | |
| SCHEMBL2956433 | 0.73 | IGF1R (0.60) | IGF1REGFRERBB2 | |
| SCHEMBL2965040 | 0.73 | IGF1R (0.60) | IGF1REGFRERBB2 | |
| SCHEMBL2959491 | 0.73 | IGF1R (0.59) | IGF1REGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772231-B2 | Substituted pyrazolo[3,4-d]pyrimidines as protein kinase inhibitors | ABBOTT LABORATORIES (US) | 2010-08-10 | — | — | US | claimed |