Lespedezaflavanone B

Lespedezaflavanone B

SCHEMBL29624618

CC(C)=CCc1cc([C@@H]2CC(=O)c3c(O)cc(O)c(CC=C(C)C)c3O2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 4/20 1.00
ABCG2 Q9UNQ0 5/20 0.78
ESR1 P03372 3/20 0.78
ESR2 Q92731 2/20 0.78
AKR1B10 O60218 2/20 0.78
AKR1B1 P15121 2/20 0.78
CACNA1G O43497 1/20 0.78
CACNA1H O95180 1/20 0.78
MAOA P21397 1/20 0.78
PDE5A O76074 1/20 0.78
CYP1A1 P04798 1/20 0.77
CYP1B1 Q16678 1/20 0.77
CYP3A4 P08684 1/20 0.75
CYP2D6 P10635 1/20 0.75
CYP2C9 P11712 1/20 0.75
ACHE P22303 1/20 0.75
CYP2C19 P33261 1/20 0.75
CYP19A1 P11511 4/20 0.73
PDPK1 O15530 1/20 0.64
PRKCA P17252 1/20 0.64

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lespedezaflavanone B SCHEMBL27013477 1.00 PTPN1 (1.00) PTPN1ABCG2ESR1ESR2AKR1B10
Lespedezaflavanone B SCHEMBL1171210 1.00 PTPN1 (1.00) PTPN1ABCG2ESR1ESR2AKR1B10
SCHEMBL1170921 0.91 PTPN1 (0.84) PTPN1ABCG2ESR1ESR2AKR1B10
SCHEMBL29402380 0.90 PTPN1 (0.82) PTPN1ABCG2ESR1ESR2AKR1B10
SCHEMBL27013484 0.89 PTPN1 (0.80) PTPN1ABCG2ESR1ESR2AKR1B10
SCHEMBL29726937 0.89 ABCG2 (0.85) PTPN1ABCG2ESR1ESR2AKR1B10
Sophoraflavanone B SCHEMBL1171435 0.88 ESR1 (1.00) PTPN1ABCG2ESR1ESR2AKR1B10
Sophoraflavanone B SCHEMBL29396586 0.88 ESR1 (1.00) PTPN1ABCG2ESR1ESR2AKR1B10
Sophoraflavanone B SCHEMBL14304885 0.88 ESR1 (1.00) PTPN1ABCG2ESR1ESR2AKR1B10
Sophoraflavanone B SCHEMBL147316 0.88 ESR1 (1.00) PTPN1ABCG2ESR1ESR2AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120607974-A Method for synthesizing chicoric acid metabolic engineering strain by Saccharomyces cerevisiae from glucose and tartaric acid 浙江工业大学 2025-09-09 CN disclosed
US-20250177523-A1 MULTISPECIFIC ANTIGEN-BINDING PROTEINS GENENTECH, INC. (US) 2025-06-05 US disclosed
US-20250032610-A1 MULTISPECIFIC ANTIGEN-BINDING PROTEINS GENENTECH, INC. (US) 2025-01-30 US disclosed
US-12053525-B2 Multispecific antigen-binding proteins GENENTECH, INC. (US) 2024-08-06 US disclosed
CN-117587150-A KASP molecular marker primer for detecting cigar tobacco leaf number and application thereof 中国农业科学院烟草研究所(中国烟草总公司青州烟草研究所) 2024-02-23 CN disclosed
WO-2023187599-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR THE TREATMENT OF VIRAL DISEASES DIDENKO KIRILL (MX) 2023-10-05 WO disclosed
CN-116063543-A Multispecific antigen-binding proteins 豪夫迈·罗氏有限公司 2023-05-05 CN disclosed
US-20220409725-A1 MULTISPECIFIC ANTIGEN-BINDING PROTEINS GENENTECH, INC. (US) 2022-12-29 US disclosed
CN-107787332-B Multispecific antigen binding proteins 豪夫迈·罗氏有限公司 2022-09-09 CN disclosed
CN-112725241-B Pseudomonas chlororaphis and application thereof in prevention and treatment of leaf spot of phomopsis stolonifera 中国农业科学院蔬菜花卉研究所 2022-08-30 CN disclosed
CN-112920960-B Method for increasing palmitoleic acid content of saccharomyces cerevisiae 北京化工大学 2022-07-26 CN disclosed
CN-114512177-B Method and device for tracing pedigree of crop breeding material source 北京市农林科学院信息技术研究中心 2022-07-22 CN disclosed
CN-114464248-B Method and system for calculating genetic relationship in breeding material family 北京市农林科学院信息技术研究中心 2022-07-01 CN disclosed
CN-114512177-A Method and device for tracing pedigree of crop breeding material source 北京市农林科学院信息技术研究中心 2022-05-17 CN disclosed
CN-114464248-A Method and system for calculating genetic relationship in breeding material family 北京市农林科学院信息技术研究中心 2022-05-10 CN disclosed