Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | MAP2K1 | Q02750 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.35 |
| ▸ | JAK2 | O60674 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | CSF1R | P07333 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | LTK | P29376 | 1/20 | 0.35 |
| ▸ | GRK5 | P34947 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20209204 | 1.00 | NPSR1 (0.40) | NPSR1MAPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20188999 | 0.83 | NPSR1 (0.41) | NPSR1MAPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL20189161 | 0.82 | MAPK1 (0.41) | NPSR1MAPK1KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL29625123 | 0.82 | NPSR1 (0.40) | NPSR1KDM4EALDH1A1SMN1; SMN2MAP2K1 | |
| SCHEMBL20191162 | 0.82 | NPSR1 (0.40) | NPSR1KDM4EALDH1A1SMN1; SMN2MAP2K1 | |
| SCHEMBL30675211 | 0.74 | NR4A2 (0.40) | NPSR1MAPK1KDM4EL3MBTL1NR4A2 | |
| SCHEMBL21060003 | 0.74 | NR4A2 (0.40) | NPSR1MAPK1KDM4EL3MBTL1NR4A2 | |
| SCHEMBL20187674 | 0.73 | MAPT (0.38) | MAPK1 | |
| SCHEMBL28353230 | 0.71 | NPSR1 (0.54) | NPSR1KDM4EALDH1A1SMN1; SMN2MAP2K1 | |
| SCHEMBL14072998 | 0.70 | NPSR1 (0.36) | NPSR1MAPK1KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110214141-B | Benzodiazolium compounds as ENaC inhibitors | 企业治疗学有限公司 | 2022-05-31 | — | — | CN | disclosed |