Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | QDPR | P09417 | 1/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 7/20 | 0.38 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23515203 | 1.00 | PRKCI (0.42) | PRKCIKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL29625714 | 0.86 | TP53 (0.42) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL23515201 | 0.86 | TP53 (0.42) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL11206474 | 0.82 | HSD17B10 (0.60) | ALDH1A1HSD17B10HPGDBCL2L1HDAC8 | |
| SCHEMBL23515363 | 0.81 | CYP2A6 (0.48) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL29625685 | 0.81 | CYP2A6 (0.48) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL1423783 | 0.77 | HSD17B10 (0.65) | KDM4EALDH1A1HSD17B10MAPTNPC1 | |
| SCHEMBL27981067 | 0.74 | MAPT (0.48) | PRKCIKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL11371726 | 0.74 | MAPT (0.44) | PRKCIKDM4EALDH1A1HSD17B10MAPT | |
| SCHEMBL9307995 | 0.73 | BCL2L1 (0.54) | ALDH1A1HSD17B10MAPTHPGDBCL2L1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114401935-A | Ion channel antagonists/blockers and uses thereof | 上海市东方医院（同济大学附属东方医院） | 2022-04-26 | — | — | CN | disclosed |