Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH1 | O75874 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | CDK8 | P49336 | 2/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 3/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28738420 | 1.00 | IDH1 (0.56) | IDH1KMT2AMEN1MAPTLMNA | |
| SCHEMBL29625910 | 0.92 | IDH1 (0.56) | IDH1MAPTCA12CA1CA2 | |
| SCHEMBL28738385 | 0.92 | IDH1 (0.56) | IDH1MAPTCA12CA1CA2 | |
| SCHEMBL23051396 | 0.84 | KMT2A (0.58) | IDH1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23051408 | 0.83 | KMT2A (0.57) | IDH1KMT2AMEN1MAPTLMNA | |
| SCHEMBL10192075 | 0.81 | KMT2A (0.71) | IDH1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23041016 | 0.81 | KMT2A (0.55) | IDH1KMT2AMEN1MAPTLMNA | |
| SCHEMBL29625934 | 0.81 | KMT2A (0.55) | IDH1KMT2AMEN1MAPTLMNA | |
| SCHEMBL23051387 | 0.80 | MEN1 (0.55) | KMT2AMEN1MAPTLMNASMN1; SMN2 | |
| SCHEMBL23051422 | 0.80 | KMT2A (0.55) | KMT2AMEN1MAPTLMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114423743-A | Triazine derivatives for the treatment of diseases associated with neurotrophic factors | 阿泽克制药公司 | 2022-04-29 | — | — | CN | disclosed |