SCHEMBL29625940

SCHEMBL29625940

N=C(N)c1ccc2nc(CCCCCc3nc4ccc(C(=N)N)cc4[nH]3)[nH]c2c1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
F10 P00742 10/20 0.76
TPSAB1 Q15661 3/20 0.76
F2 P00734 3/20 0.76
PRSS1 P07477 2/20 0.76
PLG P00747 1/20 0.76
PLAU P00749 1/20 0.76
PRSS2 P07478 1/20 0.76
PRSS3 P35030 1/20 0.76
TPSD1 Q9BZJ3 1/20 0.74
TPSG1 Q9NRR2 1/20 0.74
F7 P08709 2/20 0.67
MAPT P10636 2/20 0.61
PKM P14618 2/20 0.61
KDM4E B2RXH2 1/20 0.61
MEN1 O00255 1/20 0.61
KMT2A Q03164 1/20 0.61
TDP1 Q9NUW8 1/20 0.61
L3MBTL1 Q9Y468 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28757174 1.00 F10 (0.76) F10TPSAB1F2PRSS1PLG
SCHEMBL29503461 0.92 F10 (0.82) F10TPSAB1F2PRSS1PLG
SCHEMBL548319 0.88 F10 (0.58) F10TPSAB1F2PRSS1PLG
SCHEMBL27639306 0.87 F10 (0.74) F10TPSAB1F2PRSS1PLG
SCHEMBL871141 0.86 F10 (1.00) F10TPSAB1F2PRSS1PLG
SCHEMBL29361696 0.86 F10 (1.00) F10TPSAB1F2PRSS1PLG
SCHEMBL7483678 0.85 F10 (0.85) F10TPSAB1F2PRSS1PLG
SCHEMBL548407 0.84 F10 (0.60) F10TPSAB1F2PRSS1PLG
SCHEMBL27659973 0.84 F10 (0.78) F10TPSAB1F2PRSS1PLG
SCHEMBL7475343 0.81 F10 (0.75) F10TPSAB1F2PRSS1PLG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250258182-A1 ROCKY MOUNTAIN SPOTTED FEVER DETECTION AND TREATMENT IDEXX LABORATORIES, INC. (US) 2025-08-14 US disclosed
EP-4262860-A2 ROCKY MOUNTAIN SPOTTED FEVER DETECTION AND TREATMENT IDEXX Laboratories, Inc. (US) 2023-10-25 EP disclosed
WO-2022133233-A2 ROCKY MOUNTAIN SPOTTED FEVER DETECTION AND TREATMENT IDEXX LABORATORIES, INC. (US) 2022-06-23 WO disclosed