SCHEMBL29626107

SCHEMBL29626107

CN(C)C(=O)N1CCC(c2cc(-c3ccc(NC(=O)c4cccn(-c5ccccc5)c4=O)cc3F)c3c(N)ncnn23)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYRO3 Q06418 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19377545 1.00 TYRO3 (1.00) TYRO3
SCHEMBL19377562 0.95 TYRO3 (1.00) TYRO3
SCHEMBL29625546 0.95 TYRO3 (1.00) TYRO3
SCHEMBL31067812 0.93 TYRO3 (1.00) TYRO3
SCHEMBL19377668 0.93 TYRO3 (1.00) TYRO3
SCHEMBL26613611 0.93 TYRO3 (0.90) TYRO3
SCHEMBL19377730 0.92 TYRO3 (1.00) TYRO3
SCHEMBL31067838 0.91 TYRO3 (1.00) TYRO3
SCHEMBL19377569 0.91 TYRO3 (1.00) TYRO3
SCHEMBL19377743 0.91 TYRO3 (0.89) TYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456175-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-09-03 — — CN claimed
CN-114456175-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-09-03 — — CN disclosed
CN-114456176-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-08-30 — — CN disclosed
CN-114456176-A Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2022-05-10 — — CN disclosed
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