SCHEMBL29626119

SCHEMBL29626119

Nc1ncnn2c(C3CCC(O)CC3)cc(-c3ccc(NC(=O)c4cccn(-c5ccc(F)cc5)c4=O)cc3F)c12

nearest known ligand 0.91

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ TYRO3 Q06418 20/20 0.91

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19377758 1.00 TYRO3 (0.91) TYRO3
SCHEMBL31051666 1.00 TYRO3 (0.91) TYRO3
SCHEMBL19377965 1.00 TYRO3 (0.91) TYRO3
SCHEMBL19377709 1.00 TYRO3 (0.91) TYRO3
SCHEMBL31051662 1.00 TYRO3 (0.91) TYRO3
SCHEMBL31051665 0.95 TYRO3 (1.00) TYRO3
SCHEMBL19377870 0.95 TYRO3 (1.00) TYRO3
SCHEMBL31051657 0.95 TYRO3 (1.00) TYRO3
SCHEMBL19377628 0.95 TYRO3 (1.00) TYRO3
SCHEMBL19377627 0.95 TYRO3 (1.00) TYRO3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114456175-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-09-03 — — CN claimed
CN-114456175-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-09-03 — — CN disclosed
CN-114456176-B Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2024-08-30 — — CN disclosed
CN-114456176-A Pyrrolotriazine compounds as TAM inhibitors 因赛特公司 2022-05-10 — — CN disclosed
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