Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 4/20 | 1.00 |
| ▸ | MERTK | Q12866 | 3/20 | 0.81 |
| ▸ | TYRO3 | Q06418 | 16/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377558 | 1.00 | AXL (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL19377787 | 0.90 | AXL (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL31067842 | 0.84 | AXL (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL19377703 | 0.84 | AXL (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL21923073 | 0.84 | TYRO3 (0.88) | AXLMERTKTYRO3 | |
| SCHEMBL19429691 | 0.84 | TYRO3 (0.88) | AXLMERTKTYRO3 | |
| SCHEMBL19429630 | 0.83 | TYRO3 (0.89) | AXLMERTKTYRO3 | |
| SCHEMBL19377569 | 0.83 | TYRO3 (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL31067838 | 0.83 | TYRO3 (1.00) | AXLMERTKTYRO3 | |
| SCHEMBL19377628 | 0.83 | TYRO3 (1.00) | AXLTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456176-B | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114456176-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |