Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AXL | P30530 | 13/20 | 0.66 |
| ▸ | MERTK | Q12866 | 10/20 | 0.66 |
| ▸ | TYRO3 | Q06418 | 11/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29626173 | 0.91 | TYRO3 (0.66) | AXLMERTKTYRO3 | |
| SCHEMBL29626277 | 0.90 | AXL (0.63) | AXLMERTKTYRO3 | |
| SCHEMBL29626190 | 0.83 | AXL (0.62) | AXLMERTKTYRO3 | |
| SCHEMBL29626112 | 0.83 | AXL (0.70) | AXLMERTKTYRO3 | |
| SCHEMBL29626196 | 0.83 | TYRO3 (0.69) | AXLMERTKTYRO3 | |
| SCHEMBL29626246 | 0.83 | TYRO3 (0.69) | AXLMERTKTYRO3 | |
| SCHEMBL29626168 | 0.82 | AXL (0.70) | AXLMERTKTYRO3 | |
| SCHEMBL29626133 | 0.82 | TYRO3 (0.70) | AXLMERTKTYRO3 | |
| SCHEMBL29626159 | 0.82 | TYRO3 (0.71) | AXLMERTKTYRO3 | |
| SCHEMBL29626162 | 0.80 | TYRO3 (0.62) | AXLMERTKTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456175-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456176-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |