Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 12/20 | 0.60 |
| ▸ | AXL | P30530 | 2/20 | 0.60 |
| ▸ | TYRO3 | Q06418 | 10/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19377712 | 0.86 | MERTK (0.72) | MERTKAXLTYRO3 | |
| SCHEMBL29626157 | 0.86 | MERTK (0.71) | MERTKAXLTYRO3 | |
| SCHEMBL26613641 | 0.85 | MERTK (0.72) | MERTKAXLTYRO3 | |
| SCHEMBL29626265 | 0.84 | TYRO3 (0.71) | MERTKAXLTYRO3 | |
| SCHEMBL19377575 | 0.83 | TYRO3 (0.75) | MERTKAXLTYRO3 | |
| SCHEMBL29626102 | 0.83 | MERTK (0.65) | MERTKAXLTYRO3 | |
| SCHEMBL29626150 | 0.83 | MERTK (0.68) | MERTKAXLTYRO3 | |
| SCHEMBL29626124 | 0.83 | MERTK (0.67) | MERTKAXLTYRO3 | |
| SCHEMBL29626188 | 0.82 | MERTK (0.72) | MERTKAXLTYRO3 | |
| SCHEMBL29626131 | 0.82 | MERTK (0.68) | MERTKAXLTYRO3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114456175-B | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2024-09-03 | — | — | CN | disclosed |
| CN-114456176-B | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2024-08-30 | — | — | CN | disclosed |
| CN-114456175-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |
| CN-114456176-A | Pyrrolotriazine compounds as TAM inhibitors | 因赛特公司 | 2022-05-10 | — | — | CN | disclosed |