Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CBLB | Q13191 | 19/20 | 0.46 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29640068 | 1.00 | CBLB (0.46) | CBLBALDH1A2ALDH1A1ALDH1A3 | |
| SCHEMBL22944997 | 1.00 | CBLB (0.46) | CBLBALDH1A2ALDH1A1ALDH1A3 | |
| SCHEMBL28741775 | 1.00 | CBLB (0.46) | CBLBALDH1A2ALDH1A1ALDH1A3 | |
| SCHEMBL28741835 | 0.92 | CBLB (0.47) | CBLB | |
| SCHEMBL22945410 | 0.92 | CBLB (0.47) | CBLB | |
| SCHEMBL22945291 | 0.89 | CBLB (0.52) | CBLB | |
| SCHEMBL22945301 | 0.89 | CBLB (0.52) | CBLB | |
| SCHEMBL28741797 | 0.89 | CBLB (0.52) | CBLB | |
| SCHEMBL29626650 | 0.89 | CBLB (0.52) | CBLB | |
| SCHEMBL22945832 | 0.87 | CBLB (0.53) | CBLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4003965-A1 | UREA, AMIDE, AND SUBSTITUTED HETEROARYL COMPOUNDS FOR CBL-B INHIBITION | Nurix Therapeutics, Inc. (US) | 2022-06-01 | — | — | EP | disclosed |