Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 6/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8004853 | 1.00 | GSK3B (0.57) | GSK3BPTPN1MAPTALDH1A1PKM | |
| SCHEMBL12609858 | 0.85 | GSK3B (0.53) | GSK3BMAPTALDH1A1PKMMEN1 | |
| SCHEMBL5054876 | 0.85 | GSK3B (0.57) | GSK3BPTPN1 | |
| SCHEMBL29514695 | 0.84 | GSK3B (0.61) | GSK3BPTPN1 | |
| SCHEMBL747174 | 0.84 | GSK3B (0.61) | GSK3BPTPN1 | |
| SCHEMBL4889600 | 0.83 | MAPT (0.49) | MAPTALDH1A1PKMMEN1LMNA | |
| Bromide SCHEMBL5722043 | 0.82 | GSK3B (0.59) | GSK3BPTPN1 | |
| SCHEMBL3995406 | 0.82 | GSK3B (0.59) | GSK3BPTPN1 | |
| SCHEMBL6514586 | 0.81 | GSK3B (0.57) | GSK3BPTPN1LMNA | |
| SCHEMBL11736603 | 0.80 | KMT2A (0.49) | MAPTALDH1A1PKMMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3997096-A1 | NEW HETEROCYCLIC COMPOUNDS | F. Hoffmann-La Roche AG (CH) | 2022-05-18 | — | — | EP | disclosed |