Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 17/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607086 | 1.00 | PDE3A (0.43) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL29628658 | 0.92 | PDE3A (0.43) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607195 | 0.92 | PDE3A (0.43) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607188 | 0.89 | PDE3A (0.45) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL29628768 | 0.89 | PDE3A (0.45) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL28743785 | 0.88 | PDE3A (0.44) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607124 | 0.88 | PDE3A (0.44) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607305 | 0.87 | PDE3A (0.44) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607359 | 0.87 | PDE3A (0.43) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL29628738 | 0.87 | PDE3A (0.44) | PDE3APDE4BPDE3BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | claimed |
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |