Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.58 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | GPR84 | Q9NQS5 | 8/20 | 0.54 |
| ▸ | FDPS | P14324 | 4/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FAAH | O00519 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL510814 | 1.00 | FFAR1 (0.58) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL16683837 | 1.00 | FFAR1 (0.58) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL77285 | 0.97 | FFAR1 (0.61) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL22395574 | 0.97 | FFAR1 (0.61) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL7661582 | 0.97 | FFAR1 (0.61) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL7670933 | 0.97 | FFAR1 (0.61) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL12152020 | 0.97 | FFAR1 (0.61) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL105856 | 0.97 | FFAR1 (0.61) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL2990323 | 0.97 | FFAR1 (0.61) | FFAR1FFAR4NFKB1GPR84FDPS | |
| SCHEMBL378816 | 0.97 | FFAR1 (0.61) | FFAR1FFAR4NFKB1GPR84FDPS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |
| CN-110036001-B | Benzo [ b ] thiophene compounds as STING agonists | 默沙东公司 | 2022-03-22 | — | — | CN | disclosed |