Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 18/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.46 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.45 |
| ▸ | PDE4A | P27815 | 2/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2845195 | 1.00 | PBRM1 (0.47) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL29628642 | 0.89 | PBRM1 (0.45) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL20607178 | 0.89 | PBRM1 (0.45) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL20607501 | 0.89 | PBRM1 (0.45) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL20607245 | 0.88 | PDE3A (0.49) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL29628609 | 0.86 | PDE3A (0.50) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL20607340 | 0.86 | PDE3A (0.50) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL20607041 | 0.86 | PDE3A (0.47) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL29628659 | 0.85 | PDE3A (0.42) | PBRM1PDE3APDE3BPDE4BPDE4A | |
| SCHEMBL20607255 | 0.85 | PDE3A (0.42) | PBRM1PDE3APDE3BPDE4BPDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |