Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 3/20 | 0.40 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.40 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TNF | P01375 | 3/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607466 | 1.00 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL29628801 | 0.88 | FFAR1 (0.37) | HTTMAPTGRM2LMNAMAPK1 | |
| SCHEMBL20607176 | 0.88 | FFAR1 (0.37) | HTTMAPTGRM2LMNAMAPK1 | |
| SCHEMBL20607313 | 0.85 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL29628815 | 0.85 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL20607103 | 0.85 | PDE4D (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL29628757 | 0.85 | PDE4D (0.40) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL20607171 | 0.85 | HTT (0.44) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL29628740 | 0.85 | HTT (0.44) | PDE4APDE4BPDE4CPDE4DHTT | |
| SCHEMBL20607434 | 0.82 | GRM2 (0.34) | PDE4APDE4BPDE4CPDE4DHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |