Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3A | Q14432 | 19/20 | 0.48 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.48 |
| ▸ | PDE3B | Q13370 | 6/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20607376 | 1.00 | PDE3A (0.48) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607360 | 1.00 | PDE3A (0.48) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL29628228 | 1.00 | PDE3A (0.48) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607353 | 0.92 | PDE3A (0.47) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607393 | 0.92 | PDE3A (0.47) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607162 | 0.91 | PDE3A (0.46) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607131 | 0.91 | PDE3A (0.46) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607397 | 0.90 | PDE3A (0.50) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL22067551 | 0.90 | PDE3A (0.50) | PDE3APDE4BPDE3BPDE4APDE4C | |
| SCHEMBL20607247 | 0.90 | PDE3A (0.46) | PDE3APDE4BPDE3BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4709388-A1 | INHIBITOR OF MEGAKARYOCYTE DIFFERENTIATION AND MATURATION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2026-03-18 | — | — | EP | claimed |
| WO-2024232361-A1 | INHIBITOR OF MEGAKARYOCYTE DIFFERENTIATION AND MATURATION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-14 | — | — | WO | claimed |
| EP-4709388-A1 | INHIBITOR OF MEGAKARYOCYTE DIFFERENTIATION AND MATURATION | Otsuka Pharmaceutical Co., Ltd. (JP) | 2026-03-18 | — | — | EP | disclosed |
| WO-2024232361-A1 | INHIBITOR OF MEGAKARYOCYTE DIFFERENTIATION AND MATURATION | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2024-11-14 | — | — | WO | disclosed |
| CN-108779076-B | 5-methyl-6-phenyl-4, 5-dihydro-2H-pyridazin-3-one derivatives | 大塚制药株式会社 | 2022-05-03 | — | — | CN | disclosed |