SCHEMBL29628893

SCHEMBL29628893

C(#Cc1c2ccccc2nc2ccccc12)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.57
ALDH1A1 P00352 4/20 0.57
APP P05067 1/20 0.52
ADORA2A P29274 1/20 0.52
SMN1; SMN2 Q16637 4/20 0.46
HPGD P15428 3/20 0.46
GLA P06280 3/20 0.46
MAOA P21397 2/20 0.46
KCNH2 Q12809 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
CASP1 P29466 2/20 0.46
CASP7 P55210 2/20 0.46
HSD17B10 Q99714 2/20 0.46
CHRM2 P08172 1/20 0.46
ADRA2A P08913 1/20 0.46
ADORA3 P0DMS8 1/20 0.46
CHRM1 P11229 1/20 0.46
NQO2 P16083 1/20 0.46
DRD1 P21728 1/20 0.46
ACHE P22303 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17423201 1.00 KDM4E (0.57) KDM4EALDH1A1APPADORA2ASMN1; SMN2
SCHEMBL29357652 0.84 APP (0.67) KDM4EALDH1A1APPADORA2ASMN1; SMN2
SCHEMBL55761 0.84 APP (0.67) KDM4EALDH1A1APPADORA2ASMN1; SMN2
SCHEMBL28392347 0.78 APP (0.52) KDM4EALDH1A1APPADORA2ASMN1; SMN2
SCHEMBL13156621 0.78 APP (0.52) KDM4EALDH1A1APPADORA2ASMN1; SMN2
SCHEMBL442909 0.77 APP (0.50) KDM4EALDH1A1APPADORA2ASMN1; SMN2
SCHEMBL18091340 0.77 APP (0.50) KDM4EALDH1A1APPADORA2ASMN1; SMN2
SCHEMBL13156676 0.76 APP (0.44) KDM4EALDH1A1APPADORA2ASMN1; SMN2
SCHEMBL5683034 0.76 APP (0.55) KDM4EALDH1A1APPSMN1; SMN2HPGD
SCHEMBL3796509 0.75 APP (0.80) KDM4EALDH1A1APPSMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113121439-B Compound, pharmaceutical composition, medicine and application of compound, pharmaceutical composition and medicine in preparation of antibacterial product 山东大学 2022-05-03 CN disclosed