Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 6/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29629113 | 0.91 | CA12 (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL29577122 | 0.88 | CA12 (0.59) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7205674 | 0.87 | CA12 (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7205667 | 0.87 | CA12 (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL19117207 | 0.87 | CA12 (0.60) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| Hydrochloric Acid SCHEMBL29544235 | 0.87 | CA12 (0.58) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7211984 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL7211986 | 0.86 | KDM4E (0.52) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL5672583 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1HPGDHSD17B10MEN1 | |
| SCHEMBL6045246 | 0.86 | TDP1 (0.48) | KDM4EALDH1A1HPGDHSD17B10MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115611823-B | 1,2, 4-Triazole-phenyl hydroxamic acid compound, preparation method and application | 新天地医药技术研究院(郑州)有限公司 | 2024-09-27 | — | — | CN | disclosed |
| CN-115611823-A | 1,2, 4-triazole-phenyl hydroxamic acid compound, preparation method and application | 新天地医药技术研究院(郑州)有限公司 | 2023-01-17 | — | — | CN | disclosed |
| CN-112250638-B | 1, 3-diaryl-1, 2, 4-triazole compound and preparation method and application thereof | 郑州大学 | 2022-05-03 | — | — | CN | disclosed |