SCHEMBL29628985

SCHEMBL29628985

Fc1cccc(-c2cccc(-c3cccc(F)c3)c2)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 3/20 0.65
ESR2 Q92731 1/20 0.65
CYP11B2 P19099 2/20 0.50
ACHE P22303 1/20 0.50
CYP17A1 P05093 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP11B1 P15538 1/20 0.50
IDO1 P14902 2/20 0.48
NOTUM Q6P988 1/20 0.48
HSD17B1 P14061 1/20 0.48
HSD17B2 P37059 1/20 0.48
NFE2L2 Q16236 1/20 0.48
PTPN1 P18031 1/20 0.47
KDM4E B2RXH2 2/20 0.47
CHRNB4 P30926 1/20 0.47
CHRNA3 P32297 1/20 0.47
NISCH Q9Y2I1 1/20 0.47
MEN1 O00255 1/20 0.47
MAPT P10636 1/20 0.47
KMT2A Q03164 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16605626 1.00 TAAR1 (0.65) TAAR1ESR2CYP11B2ACHECYP17A1
SCHEMBL16605628 1.00 TAAR1 (0.65) TAAR1ESR2CYP11B2ACHECYP17A1
SCHEMBL198702 0.97 TAAR1 (0.68) TAAR1ESR2CYP11B2ACHECYP17A1
SCHEMBL27652491 0.92 TAAR1 (0.64) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL30704326 0.92 TAAR1 (0.64) TAAR1ESR2CYP11B2CYP17A1CYP3A4
SCHEMBL28102063 0.89 TAAR1 (0.61) TAAR1ESR2CYP11B2CYP17A1CYP3A4
Biphenyl SCHEMBL25183774 0.88 TAAR1 (0.67) TAAR1ESR2CYP11B2ACHECYP17A1
SCHEMBL200605 0.88 TAAR1 (0.67) TAAR1ESR2CYP11B2ACHECYP17A1
SCHEMBL17082215 0.88 TAAR1 (0.60) TAAR1ESR2CYP11B2ACHECYP17A1
SCHEMBL29451178 0.88 TAAR1 (0.67) TAAR1ESR2CYP11B2ACHECYP17A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114621045-A Method for synthesizing polyaromatic hydrocarbon from aryl formaldehyde 长沙资材科技有限公司 2022-06-14 CN disclosed