SCHEMBL29629485

SCHEMBL29629485

CC(=O)Cc1c[nH]c2ccccc12

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 7/20 0.68
KMT2A Q03164 7/20 0.68
MAPT P10636 5/20 0.68
SMN1; SMN2 Q16637 3/20 0.68
ALDH1A1 P00352 3/20 0.68
KDM4E B2RXH2 3/20 0.68
HPGD P15428 1/20 0.68
PKM P14618 2/20 0.65
LMNA P02545 3/20 0.64
SLC6A2 P23975 1/20 0.64
FNTA P49354 1/20 0.64
FNTB P49356 1/20 0.64
CYP2C19 P33261 3/20 0.60
CYP1A2 P05177 2/20 0.60
TSHR P16473 2/20 0.60
BLM P54132 1/20 0.60
CYP3A4 P08684 3/20 0.58
AHR P35869 1/20 0.58
GPR84 Q9NQS5 1/20 0.58
TDP1 Q9NUW8 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL468399 1.00 MEN1 (0.68) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
SCHEMBL29407882 0.85 MAPT (0.72) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
SCHEMBL21479833 0.85 MAPT (0.72) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
SCHEMBL9531242 0.85 MEN1 (0.62) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
Indole-3-Acetic Acid SCHEMBL29350750 0.84 MEN1 (0.75) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
SCHEMBL3448734 0.84 MAPT (0.70) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
Indole-3-Acetic Acid SCHEMBL7887240 0.84 MEN1 (0.75) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
Indole-3-Acetic Acid SCHEMBL26344 0.84 MEN1 (0.75) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
SCHEMBL4856078 0.83 MEN1 (0.60) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1
Acetic Acid SCHEMBL27760596 0.83 MEN1 (0.65) MEN1KMT2AMAPTSMN1; SMN2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4423178-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2024-09-04 EP claimed
WO-2023073536-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2023-05-04 WO claimed
US-20250214996-A1 SALTS AND SOLID FORMS OF AN ESTROGEN RECEPTOR ANTAGONIST CURIA GLOBAL, INC. 2025-07-03 US disclosed
EP-4525865-A1 CRYSTALLINE FORMS OF AN ESTROGEN RECEPTOR ANTAGONIST Olema Pharmaceuticals, Inc. (US) 2025-03-26 EP disclosed
EP-4423178-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2024-09-04 EP disclosed
EP-4366734-A1 METHODS OF TREATING ESTROGEN RECEPTOR-ASSOCIATED DISEASES Olema Pharmaceuticals, Inc. (US) 2024-05-15 EP disclosed
WO-2023225354-A1 CRYSTALLINE FORMS OF AN ESTROGEN RECEPTOR ANTAGONIST OLEMA PHARMACEUTICALS, INC. (US) 2023-11-23 WO disclosed
EP-4271682-A1 METHOD OF SYNTHESIZING INDOLE COMPOUNDS 1280225 B.C. Ltd. (CA) 2023-11-08 EP disclosed
CN-116964049-A Estrogen receptor modulators 里科瑞尔姆IP控股有限责任公司 2023-10-27 CN disclosed
WO-2023073536-A1 METHOD AND COMPOSITION FOR REDUCING SOLVENT RELEASE FROM, AND REDUCING ODOR OF, AGROCHEMICAL FORMULATIONS ADAMA MAKHTESHIM LTD. (IL) 2023-05-04 WO disclosed
CN-112679495-B Estrogen receptor modulators 里科瑞尔姆IP控股有限责任公司 2023-03-28 CN disclosed
WO-2023283329-A1 METHODS OF TREATING ESTROGEN RECEPTOR-ASSOCIATED DISEASES OLEMA PHARMACEUTICALS, INC. (US) 2023-01-12 WO disclosed
EP-4114391-A1 METHODS OF TREATING ESTROGEN RECEPTOR-ASSOCIATED DISEASES Olema Pharmaceuticals, Inc. (US) 2023-01-11 EP disclosed
CN-110382496-B Substituted pyrido [3,4-b ] indoles for the treatment of cartilage disorders 赛诺菲 2022-08-09 CN disclosed
WO-2022140844-A1 METHOD OF SYNTHESIZING INDOLE COMPOUNDS 1280225 B.C. LTD. (CA) 2022-07-07 WO disclosed
EP-3993785-A1 REGIMENS OF ESTROGEN RECEPTOR ANTAGONISTS Olema Pharmaceuticals, Inc. (US) 2022-05-11 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250214996-A1 SALTS AND SOLID FORMS OF AN ESTROGEN RECEPTOR ANTAGONIST ESR1, ESR2, ESRRA MEN1 3962/4885KMT2A 1889/4885MAPT 1298/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.