SCHEMBL29630348

SCHEMBL29630348

N=C(N)NCCC[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)CN)C(=O)NCC(=O)O

nearest known ligand 0.53

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
QRFPR Q96P65 6/20 0.53
NPY4R P50391 11/20 0.51
NPY5R Q15761 8/20 0.51
NPY1R P25929 7/20 0.51
NPY2R P49146 5/20 0.51
CTSL P07711 1/20 0.47
CHRNA1 P02708 1/20 0.46
CHRNG P07510 1/20 0.46
CHRNB1 P11230 1/20 0.46
CHRND Q07001 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29590985 0.98 QRFPR (0.56) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL30121028 0.98 QRFPR (0.56) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL29591802 0.94 QRFPR (0.54) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL24713048 0.94 QRFPR (0.53) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL30481160 0.91 QRFPR (0.64) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL29447208 0.91 NPY4R (0.52) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL5598748 0.90 NPY4R (0.52) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL5598751 0.90 NPY4R (0.52) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL30692729 0.90 GNPAT (0.54) QRFPRNPY4RNPY5RNPY1RNPY2R
SCHEMBL29447211 0.90 GNPAT (0.54) QRFPRNPY4RNPY5RNPY1RNPY2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed