Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 10/20 | 0.58 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.54 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.49 |
| ▸ | CTSD | P07339 | 1/20 | 0.49 |
| ▸ | GNPAT | O15228 | 1/20 | 0.49 |
| ▸ | FOLH1 | Q04609 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30605192 | 0.94 | BACE1 (0.55) | BACE1NAALAD2BACE2CTSDGNPAT | |
| SCHEMBL30605191 | 0.94 | BACE1 (0.55) | BACE1NAALAD2BACE2CTSDGNPAT | |
| SCHEMBL30312137 | 0.92 | BACE1 (0.64) | BACE1NAALAD2BACE2CTSD | |
| SCHEMBL29575648 | 0.92 | NAALAD2 (0.56) | BACE1NAALAD2BACE2CTSDGNPAT | |
| SCHEMBL2108111 | 0.90 | GNPAT (0.60) | GNPAT | |
| SCHEMBL1711756 | 0.90 | GNPAT (0.60) | GNPAT | |
| SCHEMBL2108121 | 0.90 | GNPAT (0.60) | GNPAT | |
| SCHEMBL1711761 | 0.90 | GNPAT (0.60) | GNPAT | |
| SCHEMBL30385107 | 0.90 | GNPAT (0.52) | BACE1GNPAT | |
| SCHEMBL31720970 | 0.88 | BACE1 (0.65) | BACE1NAALAD2BACE2CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11807899-B2 | Biochemical reaction methods and reagents comprising intrinsically disordered regions | Biocrucible Limited | 2023-11-07 | — | — | US | disclosed |
| US-20220145378-A1 | BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS | Biocrucible Limited (GB) | 2022-05-12 | — | — | US | disclosed |