SCHEMBL29630725

SCHEMBL29630725

CC(C)C[C@H](NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@@H](N)CC(C)C)C(=O)O

nearest known ligand 0.57

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 9/20 0.57
BACE1 P56817 6/20 0.47
NAALAD2 Q9Y3Q0 1/20 0.46
CTSD P07339 1/20 0.45
PTPN1 P18031 2/20 0.45
BMP1 P13497 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30659898 1.00 FOLH1 (0.57) FOLH1BACE1NAALAD2CTSDPTPN1
SCHEMBL29679534 0.96 FOLH1 (0.56) FOLH1BACE1NAALAD2CTSDPTPN1
SCHEMBL29679903 0.96 FOLH1 (0.55) FOLH1BACE1NAALAD2CTSDPTPN1
SCHEMBL1674769 0.96 FOLH1 (0.50) FOLH1BACE1
SCHEMBL1674773 0.95 FOLH1 (0.63) FOLH1BACE1NAALAD2PTPN1
SCHEMBL31454946 0.93 FOLH1 (0.61) FOLH1BACE1NAALAD2CTSD
SCHEMBL30553676 0.93 FOLH1 (0.61) FOLH1BACE1NAALAD2CTSD
SCHEMBL29846196 0.93 FOLH1 (0.61) FOLH1BACE1NAALAD2CTSD
SCHEMBL30596286 0.92 BACE1 (0.52) FOLH1BACE1CTSDBMP1
SCHEMBL30903465 0.92 FOLH1 (0.49) FOLH1BACE1CTSDBMP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807899-B2 Biochemical reaction methods and reagents comprising intrinsically disordered regions Biocrucible Limited 2023-11-07 US disclosed
US-20220145378-A1 BIOCHEMICAL REACTION METHODS AND REAGENTS COMPRISING INTRINSICALLY DISORDERED REGIONS Biocrucible Limited (GB) 2022-05-12 US disclosed