Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 17/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 13/20 | 0.46 |
| ▸ | ADRA1A | P35348 | 4/20 | 0.42 |
| ▸ | HRH1 | P35367 | 4/20 | 0.42 |
| ▸ | HTR2B | P41595 | 3/20 | 0.42 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.39 |
| ▸ | TUBB | P07437 | 1/20 | 0.39 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.39 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.39 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.39 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.39 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.39 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.39 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.39 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.39 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.39 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.39 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24360048 | 0.89 | MCHR1 (0.48) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL29632347 | 0.89 | MCHR1 (0.48) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL29632342 | 0.89 | MCHR1 (0.46) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL24360023 | 0.89 | MCHR1 (0.46) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL24359996 | 0.89 | MCHR1 (0.46) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL24360370 | 0.88 | MCHR1 (0.56) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL29632421 | 0.88 | MCHR1 (0.56) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL29632418 | 0.87 | MCHR1 (0.44) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL24494052 | 0.83 | MCHR1 (0.47) | MCHR1ADRA2AADRA1AHRH1HTR2B | |
| SCHEMBL25110124 | 0.82 | GRM5 (0.48) | MCHR1ADRA2AADRA1AHRH1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116710434-A | Modulators of MAS-related G protein receptor X2 and related products and uses thereof | 伊赛恩特制药公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-4232042-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND THEIR USE | ESCIENT PHARMACEUTICALS, INC. (US) | 2023-08-30 | — | — | EP | disclosed |
| WO-2022087083-A1 | MODULATORS OF MAS-RELATED G-PROTEIN RECEPTOR X2 AND RELATED PRODUCTS AND THEIR USE | ESCIENT PHARMACEUTICALS, INC. (US) | 2022-04-28 | — | — | WO | disclosed |