Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 8/20 | 0.46 |
| ▸ | NUDT1 | P36639 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | KCNN2 | Q9H2S1 | 1/20 | 0.36 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29632634 | 0.99 | HRH4 (0.47) | HRH4NUDT1ABL1RIN1LMNA | |
| SCHEMBL29632653 | 0.93 | HRH4 (0.42) | HRH4NUDT1ABL1RIN1LMNA | |
| SCHEMBL29632672 | 0.91 | HRH4 (0.41) | HRH4NUDT1ABL1RIN1LMNA | |
| SCHEMBL29632671 | 0.90 | HRH4 (0.38) | HRH4LMNAHDAC6KDM4ETDP1 | |
| SCHEMBL12291021 | 0.89 | HRH4 (0.38) | HRH4LMNAHDAC6GAAATM | |
| SCHEMBL12291464 | 0.89 | HRH4 (0.38) | HRH4LMNAHDAC6GAAATM | |
| SCHEMBL29632639 | 0.87 | HRH4 (0.36) | HRH4ABL1RIN1LMNAHDAC6 | |
| SCHEMBL29632613 | 0.86 | HDAC6 (0.38) | HRH4NUDT1ABL1RIN1LMNA | |
| SCHEMBL29632690 | 0.83 | HRH4 (0.50) | HRH4NUDT1ABL1RIN1LMNA | |
| SCHEMBL807815 | 0.81 | JAK3 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022086284-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2022-04-28 | — | — | WO | disclosed |
| WO-2022071772-A1 | PROTEIN KINASE INHIBITOR AND USE THEREOF | (주)메디톡스 | 2022-04-07 | — | — | WO | disclosed |