SCHEMBL29633045

SCHEMBL29633045

CCOc1cc(CC(C)N)c(OC)cc1OC

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 4/20 0.80
TAAR1 Q96RJ0 2/20 0.70
HTR1A P08908 1/20 0.61
HTR2C P28335 1/20 0.61
HTR2B P41595 1/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5302319 1.00 HTR2A (0.80) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL2556573 1.00 HTR2A (0.80) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL2556577 1.00 HTR2A (0.80) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL5302329 1.00 HTR2A (0.80) HTR2ATAAR1HTR1AHTR2CHTR2B
Hydrochloric Acid SCHEMBL2761491 0.98 HTR2A (0.77) HTR2ATAAR1HTR1AHTR2CHTR2B
Hydrochloric Acid SCHEMBL2761490 0.98 HTR2A (0.77) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL5304945 0.98 HTR2A (0.77) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL5304943 0.98 HTR2A (0.77) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL5303673 0.97 HTR2A (0.74) HTR2ATAAR1HTR1AHTR2CHTR2B
SCHEMBL5305069 0.97 HTR2A (0.74) HTR2ATAAR1HTR1AHTR2CHTR2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4452986-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME Kuleon LLC (US) 2024-10-30 EP disclosed
CN-118055766-A Magic and non-magic serotonin receptor agonist and its preparing process and usage 库莱恩有限责任公司 2024-05-17 CN disclosed
WO-2023225043-A1 TRICYCLIC AND TETRACYCLIC SEROTONIN RECEPTOR MODULATORS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-11-23 WO disclosed
EP-4251181-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS Wesana Health Inc. (US) 2023-10-04 EP disclosed
EP-4251139-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE Wesana Health Inc. (US) 2023-10-04 EP disclosed
WO-2023122135-A1 SEROTONIN RECEPTOR AGONISTS AND METHODS OF MAKING AND USING THE SAME KULEON LLC (US) 2023-06-29 WO disclosed
WO-2023023298-A1 HALLUCINOGENIC AND NON-HALLUCINOGENIC COMPOUNDS AND METHODS OF MAKING AND USING THE SAME PSILOSTERICS, LLC (US) 2023-02-23 WO disclosed
WO-2022115798-A2 COMPOSITIONS AND METHODS FOR TREATING MIGRAINE WESANA HEALTH INC. (US) 2022-06-02 WO disclosed
WO-2022115796-A1 COMPOSITIONS AND METHODS FOR TREATING NEUROLOGICAL CONDITIONS WESANA HEALTH INC. (US) 2022-06-02 WO disclosed