Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | WNT3A | P56704 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | OGA | O60502 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1451524 | 1.00 | PRMT5 (0.37) | PRMT5WDR77NPC1RAB9AKMT2A | |
| SCHEMBL1451522 | 1.00 | PRMT5 (0.37) | PRMT5WDR77NPC1RAB9AKMT2A | |
| SCHEMBL1451265 | 0.92 | NPC1 (0.40) | PRMT5WDR77NPC1RAB9AKMT2A | |
| SCHEMBL1451350 | 0.92 | NPC1 (0.40) | PRMT5WDR77NPC1RAB9AKMT2A | |
| SCHEMBL1451268 | 0.92 | NPC1 (0.40) | PRMT5WDR77NPC1RAB9AKMT2A | |
| SCHEMBL13538772 | 0.88 | OGA (0.38) | PRMT5WDR77NPC1RAB9AKMT2A | |
| SCHEMBL1450816 | 0.86 | CYP19A1 (0.37) | RAB9AKMT2ATRPV1MAOAMAOB | |
| SCHEMBL1450813 | 0.86 | CYP19A1 (0.37) | RAB9AKMT2ATRPV1MAOAMAOB | |
| SCHEMBL1450673 | 0.82 | CYP11B1 (0.39) | PRMT5WDR77NPC1RAB9ACTNNB1 | |
| SCHEMBL1861927 | 0.82 | CYP11B1 (0.39) | PRMT5WDR77NPC1RAB9ACTNNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118812481-A | Process for producing heterocyclylacetamide derivative | 持田制药株式会社 | 2024-10-22 | — | — | CN | disclosed |
| CN-114206847-B | Process for producing heterocyclylacetamide derivative | 持田制药株式会社 | 2024-07-16 | — | — | CN | disclosed |
| CN-114206847-A | Process for producing heterocyclylideneacetamide derivative | 持田制药株式会社 | 2022-03-18 | — | — | CN | disclosed |