Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 4/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | ANPEP | P15144 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EDNRB | P24530 | 1/20 | 0.37 |
| ▸ | EDNRA | P25101 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269273 | 1.00 | MEN1 (0.43) | MEN1KMT2ASIGMAR1MMP3MMP8 | |
| SCHEMBL540725 | 1.00 | MEN1 (0.43) | MEN1KMT2ASIGMAR1MMP3MMP8 | |
| SCHEMBL15036610 | 1.00 | MEN1 (0.43) | MEN1KMT2ASIGMAR1MMP3MMP8 | |
| SCHEMBL29831499 | 1.00 | MEN1 (0.43) | MEN1KMT2ASIGMAR1MMP3MMP8 | |
| SCHEMBL16150008 | 1.00 | MEN1 (0.43) | MEN1KMT2ASIGMAR1MMP3MMP8 | |
| SCHEMBL16008920 | 1.00 | MEN1 (0.43) | MEN1KMT2ASIGMAR1MMP3MMP8 | |
| SCHEMBL6688800 | 1.00 | MEN1 (0.43) | MEN1KMT2ASIGMAR1MMP3MMP8 | |
| SCHEMBL4283038 | 0.85 | KDM1A (0.42) | SIGMAR1KDM1AGAAHTR2AANPEP | |
| SCHEMBL4286040 | 0.85 | KDM1A (0.42) | SIGMAR1KDM1AGAAHTR2AANPEP | |
| SCHEMBL19523452 | 0.84 | KDM1A (0.41) | SIGMAR1KDM1ATSHRNPSR1HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022103752-A1 | RAPID CONSTRUCTION OF TETRALIN, CHROMANE, AND INDANE MOTIFS VIA CYCLATIVE C-H/C-H COUPLING | THE SCRIPPS RESEARCH INSTITUTE (US) | 2022-05-19 | — | — | WO | disclosed |