SCHEMBL29633490

SCHEMBL29633490

CC(C)(C)OC(=O)[C@H](CSSC[C@@H](NC(=O)OCC1c2ccccc2-c2ccccc21)C(=O)OC(C)(C)C)NC(=O)OCC1c2ccccc2-c2ccccc21

nearest known ligand 0.55

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MDM4 O15151 2/20 0.52
TP53 P04637 2/20 0.52
MDM2 Q00987 1/20 0.48
CASP3 P42574 1/20 0.47
KMT2A Q03164 1/20 0.47
SLC17A5 Q9NRA2 1/20 0.47
EPHX2 P34913 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8447035 1.00 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL21219839 1.00 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL29398297 1.00 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL15788340 1.00 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL13640175 0.96 MDM4 (0.49) MDM4TP53MDM2CASP3KMT2A
SCHEMBL30206885 0.94 MDM4 (0.47) MDM4TP53MDM2CASP3KMT2A
SCHEMBL27008576 0.93 MDM4 (0.49) MDM4TP53MDM2CASP3KMT2A
SCHEMBL27129147 0.93 MDM4 (0.49) MDM4TP53MDM2CASP3KMT2A
SCHEMBL10310984 0.93 MDM4 (0.52) MDM4TP53MDM2CASP3KMT2A
SCHEMBL29746914 0.91 MDM4 (0.50) MDM4TP53MDM2CASP3KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4172142-A1 BRANCHED LIPID COMPOUNDS Ena Respiratory Pty Ltd (AU) 2023-05-03 EP disclosed
EP-4157255-A1 TREATMENT OF CORONAVIRUS Ena Respiratory Pty Ltd (AU) 2023-04-05 EP disclosed
WO-2023028661-A1 FORMULATION Ena Respiratory Pty Ltd (AU) 2023-03-09 WO disclosed
EP-4025203-A1 CANCER TREATMENT Axelia Oncology Pty Ltd (AU) 2022-07-13 EP disclosed
EP-4025204-A1 CANCER IMMUNOTHERAPY Axelia Oncology Pty Ltd (AU) 2022-07-13 EP disclosed
EP-3990428-A1 NOVEL MOLECULES Axelia Oncology Pty Ltd (AU) 2022-05-04 EP disclosed