Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 3/20 | 0.51 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.46 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.46 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | CTSA | P10619 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.44 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.44 |
| ▸ | KIT | P10721 | 1/20 | 0.44 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.44 |
| ▸ | PGR | P06401 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | AGPAT2 | O15120 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.43 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5099550 | 0.86 | PDE4D (0.56) | PDE4BPTGES2PDE4DMAPK10ERN1 | |
| SCHEMBL24518295 | 0.82 | PTGES2 (0.47) | PDE4BPTGES2PDE4DMAPK10ERN1 | |
| SCHEMBL3759371 | 0.81 | PTGDR2 (0.57) | PTGES2PDE4DMAPK10ERN1SMN1; SMN2 | |
| SCHEMBL29634149 | 0.81 | PTGDR2 (0.57) | PTGES2PDE4DMAPK10ERN1SMN1; SMN2 | |
| SCHEMBL15425109 | 0.80 | KDM4E (0.55) | MAPK10FYNNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL24017210 | 0.80 | FYN (0.56) | PDE4BPDGFRBPDGFRAFYN | |
| SCHEMBL31067143 | 0.79 | MEN1 (0.46) | CTSARAB9A | |
| SCHEMBL20898099 | 0.79 | MEN1 (0.46) | CTSARAB9A | |
| SCHEMBL16574087 | 0.78 | MEN1 (0.43) | AGPAT2 | |
| SCHEMBL20573238 | 0.78 | PTGDR2 (0.45) | PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113214178-B | 3-aryl substituted anthranilic anhydride derivative and preparation method thereof | 广东工业大学 | 2022-05-13 | — | — | CN | disclosed |