Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 3/20 | 0.66 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | AKR1B10 | O60218 | 2/20 | 0.66 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.66 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.66 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.66 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.66 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.66 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.66 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 1/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.66 |
| ▸ | OSBP | P22059 | 1/20 | 0.63 |
| ▸ | OSBP2 | Q969R2 | 1/20 | 0.63 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.56 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28512250 | 1.00 | EPHA2 (0.66) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL11571094 | 0.91 | OSBP (0.75) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL11785013 | 0.91 | OSBP (0.75) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL28731645 | 0.91 | OSBP (0.75) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL11524136 | 0.91 | OSBP (0.75) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL28529381 | 0.88 | EPHA2 (0.64) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL27660232 | 0.88 | EPHA2 (0.64) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL28222292 | 0.87 | GPBAR1 (0.71) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL7528751 | 0.87 | GPBAR1 (0.71) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 | |
| SCHEMBL15353571 | 0.86 | GPBAR1 (0.67) | EPHA2GPBAR1HSD17B10TDP1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3593143-B1 | A SCREENING METHOD FOR CEREBROTENDINOUS XANTHOMATOSIS USING BILE ALCOHOL GLUCURONIDES AND METABOLITE RATIOS | Stichting Amsterdam UMC (NL) | 2024-11-27 | — | — | EP | claimed |
| CN-110612448-B | Method for screening for xanthomatosis of brain tendons using ratio of bile alcohol glucuronide and metabolite | 阿姆斯特丹大学学术医学中心 | 2023-06-13 | — | — | CN | claimed |
| US-11650212-B2 | Screening method for cerebrotendinous xanthomatosis using bile alcohol glucuronides and metabolite ratios | ACADEMISCH MEDISCH CENTRUM (NL) | 2023-05-16 | — | — | US | claimed |
| EP-4219735-B1 | METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR | ABBOTT DIABETES CARE (US) | 2026-04-01 | — | — | EP | disclosed |
| EP-4538692-A2 | METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR | Abbott Diabetes Care (US) | 2025-04-16 | — | — | EP | disclosed |
| EP-3593143-B1 | A SCREENING METHOD FOR CEREBROTENDINOUS XANTHOMATOSIS USING BILE ALCOHOL GLUCURONIDES AND METABOLITE RATIOS | Stichting Amsterdam UMC (NL) | 2024-11-27 | — | — | EP | disclosed |
| CN-118483297-A | Method and apparatus for analyte detection using electrochemical biosensors | 雅培糖尿病护理公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-110799651-B | Method and apparatus for analyte detection using electrochemical biosensors | 雅培糖尿病护理公司 | 2024-05-24 | — | — | CN | disclosed |
| US-11753222-B2 | Powdered pouch and method of making same | MONOSOL, LLC (US) | 2023-09-12 | — | — | US | disclosed |
| EP-4219735-A1 | METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR | Abbott Diabetes Care (US) | 2023-08-02 | — | — | EP | disclosed |
| CN-110612448-B | Method for screening for xanthomatosis of brain tendons using ratio of bile alcohol glucuronide and metabolite | 阿姆斯特丹大学学术医学中心 | 2023-06-13 | — | — | CN | disclosed |
| US-20230159979-A1 | TRANSDUCERS, NANOPARTICLE TRANSDUCER DEVICES AND SYSTEMS, AND RELATED METHODS OF USE | UNIVERSITY OF WASHINGTON (US) | 2023-05-25 | — | — | US | disclosed |
| US-11650212-B2 | Screening method for cerebrotendinous xanthomatosis using bile alcohol glucuronides and metabolite ratios | ACADEMISCH MEDISCH CENTRUM (NL) | 2023-05-16 | — | — | US | disclosed |
| EP-3645733-B1 | METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR | ABBOTT DIABETES CARE (US) | 2023-04-26 | — | — | EP | disclosed |
| EP-4135579-A1 | TRANSDUCERS, NANOPARTICLE TRANSDUCER DEVICES AND SYSTEMS, AND RELATED METHODS OF USE | University of Washington (US) | 2023-02-22 | — | — | EP | disclosed |
| CN-115484867-A | Transducer, nanoparticle transducer apparatus and system, and related methods of use | 华盛顿大学 | 2022-12-16 | — | — | CN | disclosed |
| US-20220260517-A1 | METHOD AND APPARATUS FOR ANALYTE DETECTION USING AN ELECTROCHEMICAL BIOSENSOR | ABBOTT DIABETES CARE INC. | 2022-08-18 | — | — | US | disclosed |
| EP-2825624-B2 | WATER SOLUBLE COMPOSITIONS INCORPORATING ENZYMES, AND METHOD OF MAKING SAME | MONOSOL LLC (US) | 2022-07-27 | — | — | EP | disclosed |
| EP-2838811-B2 | POWDERED POUCH AND METHOD OF MAKING SAME | MONOSOL LLC (US) | 2022-06-29 | — | — | EP | disclosed |
| US-11371957-B2 | Method and apparatus for analyte detection using an electrochemical biosensor | ABBOTT DIABETES CARE INC. (US) | 2022-06-28 | — | — | US | disclosed |