SCHEMBL29634185 — predicted protein targets

Predicted protein targets (top 9)

	gene	UniProt	supporting neighbours	confidence
▸	PARP1	P09874	1/20	0.43

▸	GRM2	Q14416	9/20	0.40

▸	SIRT2	Q8IXJ6	2/20	0.35

▸	SRC	P12931	1/20	0.35

▸	ELANE	P08246	1/20	0.33

▸	MEN1	O00255	1/20	0.33

▸	KMT2A	Q03164	1/20	0.33

▸	STK17B	O94768	1/20	0.33

▸	PDE5A	O76074	1/20	0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL28531562	1.00	PARP1 (0.43)	PARP1GRM2SIRT2SRCELANE
SCHEMBL29634337	0.96	PARP1 (0.43)	PARP1GRM2SIRT2SRCELANE
SCHEMBL28532501	0.96	PARP1 (0.43)	PARP1GRM2SIRT2SRCELANE
SCHEMBL29634282	0.90	PARP1 (0.46)	PARP1GRM2MEN1KMT2ASTK17B
SCHEMBL28520053	0.90	PARP1 (0.46)	PARP1GRM2MEN1KMT2ASTK17B
SCHEMBL29634216	0.86	PARP1 (0.43)	PARP1MEN1KMT2ASTK17B
SCHEMBL28738398	0.86	PARP1 (0.43)	PARP1MEN1KMT2ASTK17B
SCHEMBL26119	0.82	PARP1 (0.64)	PARP1MEN1KMT2A
SCHEMBL28524800	0.80	KDM4E (0.43)	PARP1MEN1KMT2A
SCHEMBL29634193	0.80	KDM4E (0.43)	PARP1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
CN-112442022-B	Benzoxazine-4-ketone compound, preparation method and medical application thereof	承德医学院	2022-05-20	—	—	CN	disclosed