Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.60 |
| ▸ | BACE1 | P56817 | 8/20 | 0.56 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.55 |
| ▸ | NPY1R | P25929 | 1/20 | 0.53 |
| ▸ | NPY2R | P49146 | 1/20 | 0.53 |
| ▸ | NPY4R | P50391 | 1/20 | 0.53 |
| ▸ | MME | P08473 | 2/20 | 0.53 |
| ▸ | ACE | P12821 | 2/20 | 0.53 |
| ▸ | CPA1 | P15085 | 1/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 5/20 | 0.53 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.53 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | CTSD | P07339 | 1/20 | 0.51 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6514154 | 0.94 | BACE1 (0.63) | NAALAD2BACE1BACE2NPY1RNPY2R | |
| SCHEMBL159464 | 0.93 | NAALAD2 (0.69) | NAALAD2NPY1RNPY2RNPY4RMME | |
| SCHEMBL27412431 | 0.93 | NAALAD2 (0.69) | NAALAD2NPY1RNPY2RNPY4RMME | |
| SCHEMBL159463 | 0.93 | NAALAD2 (0.69) | NAALAD2NPY1RNPY2RNPY4RMME | |
| SCHEMBL30498618 | 0.91 | BACE1 (0.65) | NAALAD2BACE1BACE2CTSD | |
| SCHEMBL31064856 | 0.90 | NAALAD2 (0.66) | NAALAD2BACE1BACE2NPY1RNPY2R | |
| SCHEMBL30436583 | 0.90 | BACE1 (0.60) | NAALAD2BACE1BACE2NPY1RNPY2R | |
| SCHEMBL29605141 | 0.90 | BACE1 (0.60) | NAALAD2BACE1BACE2NPY1RNPY2R | |
| SCHEMBL30512714 | 0.89 | NPY4R (0.58) | NAALAD2BACE1BACE2NPY1RNPY2R | |
| SCHEMBL16486435 | 0.89 | NAALAD2 (0.68) | NAALAD2BACE1BACE2NPY1RNPY2R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096103-A1 | COMBINATION OF PARA-AMINOHIPPURIC ACID (PAH) AND RADIOLABELED COMPLEXES FOR TREATING CANCER | ITM Isotopen Technologien München AG (DE) | 2022-05-12 | — | — | WO | disclosed |