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SCHEMBL29634677

SCHEMBL29634677

CC[C@H](C)[C@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](C)NC(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)CNC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](NC(=O)CNC(=O)[C@@H](N)CCC(=O)O)[C@@H](C)O)[C@@H](C)O)C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)N[C@@H](CC(C)C)C(=O)N[C@H](C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)NCC(=O)O)C(C)C

nearest known ligand 0.77

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 18/20 0.77
▸ ECE1 P42892 1/20 0.77
▸ MUS81 Q96NY9 1/20 0.77
▸ CCKBR P32239 1/20 0.73
▸ NR3C1 P04150 2/20 0.72

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29498823 1.00 GLP1R (0.77) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL30721601 1.00 GLP1R (0.77) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL30658278 0.98 GLP1R (0.77) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29942531 0.98 GLP1R (0.78) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29683237 0.98 GLP1R (0.78) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29429436 0.98 GLP1R (0.78) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29558511 0.97 GLP1R (0.77) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL31047778 0.97 GLP1R (0.78) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL29943233 0.97 GLP1R (0.79) GLP1RECE1MUS81CCKBRNR3C1
SCHEMBL31099254 0.96 GLP1R (0.78) GLP1RECE1MUS81CCKBRNR3C1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117202936-A Glucagon-like peptide compounds 诺华股份有限公司 2023-12-08 — — CN claimed
CN-117202936-A Glucagon-like peptide compounds 诺华股份有限公司 2023-12-08 — — CN disclosed
CN-110878127-B Long-acting recombinant GLP1-Fc-CD47 protein and preparation and application thereof 浙江柏拉阿图医药科技有限公司 2022-06-28 — — CN disclosed