SCHEMBL29635173

SCHEMBL29635173

COc1cccc(Nc2nc(N3CCCCCC3)nc3cn[nH]c(=O)c23)c1

nearest known ligand 0.66

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SYK P43405 18/20 0.66
JAK2 O60674 8/20 0.66

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14717515 1.00 SYK (0.66) SYKJAK2
SCHEMBL29635181 0.90 SYK (0.68) SYKJAK2
SCHEMBL14716678 0.90 SYK (0.68) SYKJAK2
SCHEMBL29635135 0.86 JAK2 (0.70) SYKJAK2
SCHEMBL14717305 0.86 JAK2 (0.70) SYKJAK2
SCHEMBL14717596 0.85 SYK (0.71) SYKJAK2
SCHEMBL14716786 0.83 SYK (0.79) SYKJAK2
SCHEMBL30604806 0.83 SYK (0.79) SYKJAK2
SCHEMBL14717381 0.83 SYK (0.63) SYKJAK2
SCHEMBL29635106 0.83 SYK (0.63) SYKJAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108707151-B Pyrimido-pyridazinone compounds and uses thereof 阿萨纳生物科技有限责任公司 2022-06-03 CN claimed
CN-108707151-B Pyrimido-pyridazinone compounds and uses thereof 阿萨纳生物科技有限责任公司 2022-06-03 CN disclosed