Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | CNR2 | P34972 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.43 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12929380 | 0.81 | KDM4E (0.61) | KDM4EALOX15LMNAALDH1A1PKM | |
| SCHEMBL242697 | 0.80 | KDM4E (0.61) | KDM4EALOX15LMNAALDH1A1PKM | |
| SCHEMBL244184 | 0.79 | KDM4E (0.66) | KDM4EALOX15LMNAALDH1A1PKM | |
| SCHEMBL244096 | 0.79 | KDM4E (0.60) | KDM4EALOX15LMNAALDH1A1PKM | |
| SCHEMBL28882232 | 0.78 | CSNK1D (0.45) | KDM4EALOX15LMNAALDH1A1TP53 | |
| SCHEMBL12279519 | 0.78 | CSNK1D (0.45) | KDM4EALOX15LMNAALDH1A1TP53 | |
| SCHEMBL13696639 | 0.78 | KDM4E (0.59) | KDM4EALOX15LMNAALDH1A1PKM | |
| SCHEMBL14590419 | 0.77 | MAPT (0.59) | KDM4EALOX15LMNAALDH1A1PKM | |
| SCHEMBL1012134 | 0.77 | KDM4E (0.58) | KDM4EALOX15LMNAALDH1A1PKM | |
| SCHEMBL1014816 | 0.76 | KDM4E (0.57) | KDM4EALOX15LMNAALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108707151-B | Pyrimido-pyridazinone compounds and uses thereof | 阿萨纳生物科技有限责任公司 | 2022-06-03 | — | — | CN | disclosed |