Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 5/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.41 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30151287 | 1.00 | MAPT (0.46) | MAPTALDH1A1NPSR1GAAMEN1 | |
| SCHEMBL22042714 | 1.00 | MAPT (0.46) | MAPTALDH1A1NPSR1GAAMEN1 | |
| SCHEMBL30151269 | 0.92 | MAPT (0.50) | MAPTALDH1A1NPSR1GAAMEN1 | |
| SCHEMBL11036785 | 0.84 | NPC1 (0.47) | MAPTNPSR1GAAMEN1KMT2A | |
| SCHEMBL30151323 | 0.84 | MAPT (0.44) | MAPTALDH1A1NPSR1GAAMEN1 | |
| SCHEMBL22042751 | 0.83 | S1PR1 (0.38) | MAPTKMT2ACYP11B2S1PR1 | |
| SCHEMBL22042745 | 0.83 | CYP1A1 (0.32) | MAPTCYP17A1CYP11B2CYP11B1 | |
| SCHEMBL22042759 | 0.83 | MAPT (0.49) | MAPTMEN1KMT2ARAB9ANPC1 | |
| SCHEMBL29635359 | 0.83 | CYP1A1 (0.32) | MAPTCYP17A1CYP11B2CYP11B1 | |
| SCHEMBL30151244 | 0.83 | MAPT (0.49) | MAPTMEN1KMT2ARAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112739689-B | Fluorine-containing pyrimidine compound and method for producing same | 优迈特株式会社 | 2022-06-03 | — | — | CN | disclosed |