Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 20/20 | 1.00 |
| ▸ | GRIN1 | Q05586 | 18/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.77 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20130013 | 1.00 | GRIN2B (1.00) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL20130015 | 0.92 | GRIN1 (1.00) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL29635507 | 0.92 | GRIN1 (1.00) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL20129967 | 0.89 | GRIN1 (1.00) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL29635424 | 0.89 | GRIN1 (1.00) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL25249841 | 0.88 | GRIN1 (0.90) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL20130014 | 0.88 | GRIN2B (1.00) | GRIN2BGRIN1 | |
| SCHEMBL20130004 | 0.87 | GRIN1 (1.00) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL29635496 | 0.87 | GRIN1 (1.00) | GRIN2BGRIN1CYP2D6 | |
| SCHEMBL20130068 | 0.87 | GRIN1 (0.96) | GRIN2BGRIN1CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114989164-A | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-09-02 | — | — | CN | claimed |
| CN-110062761-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2022-05-13 | — | — | CN | claimed |
| CN-114989164-B | Substituted 1H-imidazo [4,5-b ] pyridin-2 (3H) -ones and uses thereof | 詹森药业有限公司 | 2024-08-13 | — | — | CN | disclosed |