Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 19/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166186 | 1.00 | NAMPT (0.82) | NAMPT | |
| SCHEMBL29635817 | 0.90 | NAMPT (1.00) | NAMPT | |
| SCHEMBL20379242 | 0.90 | NAMPT (1.00) | NAMPT | |
| SCHEMBL165387 | 0.90 | NAMPT (1.00) | NAMPT | |
| SCHEMBL30927252 | 0.90 | NAMPT (1.00) | NAMPT | |
| SCHEMBL29635848 | 0.89 | NAMPT (0.86) | NAMPT | |
| SCHEMBL163243 | 0.89 | NAMPT (0.86) | NAMPT | |
| SCHEMBL163267 | 0.88 | NAMPT (0.80) | NAMPT | |
| SCHEMBL29635698 | 0.88 | NAMPT (0.80) | NAMPT | |
| SCHEMBL28112372 | 0.87 | NAMPT (0.85) | NAMPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNT, NQO1 | NAMPT 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.