Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 9/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.38 |
| ▸ | TACR1 | P25103 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL640452 | 0.87 | F2R (0.51) | F2RCNR1TMEM97POLBSMN1; SMN2 | |
| SCHEMBL640354 | 0.85 | F2R (0.56) | F2RCNR1TMEM97POLBSMN1; SMN2 | |
| SCHEMBL10234097 | 0.84 | F2R (0.59) | F2RCNR1TMEM97POLBSMN1; SMN2 | |
| SCHEMBL10234104 | 0.84 | F2R (0.56) | F2RCNR1TMEM97POLBSMN1; SMN2 | |
| SCHEMBL10234806 | 0.83 | F2R (0.54) | F2RCNR1TMEM97POLBSMN1; SMN2 | |
| SCHEMBL1581132 | 0.82 | F2R (0.53) | F2RCNR1TMEM97POLBAKR1C3 | |
| SCHEMBL642168 | 0.82 | F2R (0.60) | F2RCNR1TMEM97POLBSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL641920 | 0.81 | F2R (0.52) | F2RCNR1TMEM97POLBAKR1C3 | |
| SCHEMBL1581247 | 0.81 | F2R (0.54) | F2RCNR1TMEM97AKR1C3TACR1 | |
| SCHEMBL641880 | 0.80 | F2R (0.53) | F2RCNR1TMEM97POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2227466-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | Bayer Schering Pharma Aktiengesellschaft (DE) | 2010-09-15 | — | — | EP | disclosed |
| WO-2009068214-A2 | HETEROARYL-SUBSTITUTED PIPERIDINES | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2009-06-04 | — | — | WO | disclosed |