Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 2/20 | 0.36 |
| ▸ | CES1 | P23141 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.33 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.33 |
| ▸ | CDC25B | P30305 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.32 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22516378 | 1.00 | F10 (0.40) | F10CES2CES1BRD4SMN1; SMN2 | |
| SCHEMBL22516380 | 1.00 | F10 (0.40) | F10CES2CES1BRD4SMN1; SMN2 | |
| SCHEMBL14154941 | 1.00 | F10 (0.40) | F10CES2CES1BRD4SMN1; SMN2 | |
| SCHEMBL19813356 | 0.90 | F10 (0.39) | F10CES2CES1BRD4SMN1; SMN2 | |
| SCHEMBL11302329 | 0.83 | CYP1A2 (0.44) | F10CES2CES1BRD4SMN1; SMN2 | |
| SCHEMBL13954529 | 0.82 | EPHX1 (0.41) | CES2SMN1; SMN2 | |
| SCHEMBL14127656 | 0.82 | BRD4 (0.40) | F10CES2CES1BRD4ALDH1A1 | |
| SCHEMBL14127653 | 0.82 | BRD4 (0.40) | F10CES2CES1BRD4ALDH1A1 | |
| SCHEMBL14127655 | 0.82 | BRD4 (0.40) | F10CES2CES1BRD4ALDH1A1 | |
| SCHEMBL1543229 | 0.82 | F10 (0.36) | F10CES2CES1BRD4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112041316-B | Isoxazole O-linked carbamoyl cyclohexyl acids as LPA antagonists | 百时美施贵宝公司 | 2024-11-22 | — | — | CN | disclosed |