Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL164531 | 1.00 | NAMPT (0.77) | NAMPTCYP2C9 | |
| SCHEMBL161933 | 0.94 | NAMPT (0.83) | NAMPTCYP2C9 | |
| SCHEMBL29635738 | 0.94 | NAMPT (0.83) | NAMPTCYP2C9 | |
| SCHEMBL29635834 | 0.87 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL29635626 | 0.87 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL175663 | 0.87 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL167471 | 0.87 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL164908 | 0.86 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL29635719 | 0.86 | NAMPT (1.00) | NAMPTCYP2C9 | |
| SCHEMBL165642 | 0.86 | NAMPT (0.82) | NAMPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | VALO HEALTH, INC. (US) | 2022-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11279687-B2 | Compounds and compositions for the inhibition of NAMPT | NAMPT, NNT, NQO1 | NAMPT 1/4885CYP2C9 446/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.