Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 5/20 | 0.39 |
| ▸ | MMP2 | P08253 | 4/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1392811 | 0.69 | HRH4 (0.51) | HRH3ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL1004793 | 0.69 | HRH4 (0.48) | HRH3ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL13562340 | 0.69 | HRH3 (0.43) | HRH3ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL975741 | 0.69 | HRH3 (0.46) | HRH3ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL19658017 | 0.68 | MAPT (0.41) | ALDH1A1KDM4ESMN1; SMN2LMNAMAPT | |
| SCHEMBL28359795 | 0.68 | KDM4E (0.46) | ALDH1A1KDM4EHPGDLMNAMAPT | |
| SCHEMBL24851409 | 0.68 | HRH4 (0.50) | HRH3ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL1005493 | 0.68 | HRH3 (0.45) | HRH3ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL21310107 | 0.68 | HRH4 (0.50) | HRH3ALDH1A1KDM4ERAB9AHPGD | |
| SCHEMBL22509467 | 0.68 | HRH4 (0.50) | HRH3ALDH1A1KDM4ERAB9AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111704610-B | Pyrrolylamido pyridone compounds, preparation method and application | 上海凌达生物医药有限公司 | 2022-03-22 | — | — | CN | disclosed |