Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 17/20 | 0.79 |
| ▸ | CRBN | Q96SW2 | 17/20 | 0.79 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.60 |
| ▸ | TNF | P01375 | 1/20 | 0.60 |
| ▸ | IL1B | P01584 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.57 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2381765 | 1.00 | DDB1 (0.79) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL2382621 | 0.92 | DDB1 (0.76) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL2381262 | 0.91 | DDB1 (0.77) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29794426 | 0.91 | DDB1 (0.77) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL2381932 | 0.91 | DDB1 (0.77) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL476965 | 0.90 | DDB1 (0.73) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL30497554 | 0.90 | DDB1 (0.73) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL2382632 | 0.90 | DDB1 (0.76) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL24737277 | 0.90 | DDB1 (0.76) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL31618803 | 0.90 | DDB1 (0.76) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004251-B | Quinazoline derivative containing 2-nitroimidazole and application thereof | 郑州大学第一附属医院 | 2022-09-27 | — | — | CN | disclosed |
| CN-111704610-B | Pyrrolylamido pyridone compounds, preparation method and application | 上海凌达生物医药有限公司 | 2022-03-22 | — | — | CN | disclosed |