SCHEMBL29636358

SCHEMBL29636358

N=C(N)NCCC[C@H](NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CO)C(=O)N[C@@H](CO)C(=O)O

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 15/20 0.45
NPY1R P25929 9/20 0.45
NPY5R Q15761 8/20 0.45
NPY2R P49146 5/20 0.45
TGFBR1 P36897 1/20 0.40
NMT2 O60551 2/20 0.36
NMT1 P30419 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30446043 1.00 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RTGFBR1
SCHEMBL29576308 0.99 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RTGFBR1
SCHEMBL30571130 0.96 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL29669218 0.96 NPY4R (0.45) NPY4RNPY1RNPY5RNPY2RNMT2
SCHEMBL31522358 0.96 NPY4R (0.46) NPY4RNPY1RNPY5RNPY2R
SCHEMBL30997438 0.95 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RTGFBR1
SCHEMBL30997455 0.95 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RTGFBR1
SCHEMBL30997484 0.95 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RTGFBR1
SCHEMBL30997446 0.95 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RTGFBR1
SCHEMBL30997467 0.95 NPY4R (0.43) NPY4RNPY1RNPY5RNPY2RTGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3187508-B1 LYSOSOMAL TARGETING PEPTIDES AND USES THEREOF BIOMARIN PHARM INC (US) 2026-04-22 EP disclosed
US-20230241187-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2023-08-03 US disclosed
US-20220354934-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2022-11-10 US disclosed
US-11351231-B2 Lysosomal targeting peptides and uses thereof BIOMARIN PHARMACEUTICAL INC. (US) 2022-06-07 US disclosed