SCHEMBL29636372

SCHEMBL29636372

N=C(N)NCCC[C@H](NC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@@H](N)CCCNC(=N)N)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
NPY4R P50391 13/20 0.49
NPY1R P25929 7/20 0.49
NPY2R P49146 5/20 0.49
NPY5R Q15761 5/20 0.49
NOD1 Q9Y239 3/20 0.42
TLR2 O60603 1/20 0.38
NMT2 O60551 2/20 0.38
NMT1 P30419 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30812975 1.00 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL29789058 1.00 NPY4R (0.49) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL29669218 0.95 NPY4R (0.45) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL29400897 0.95 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL10001721 0.95 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL30438175 0.95 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL29462955 0.95 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL12533211 0.95 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL31264971 0.95 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5RNOD1
SCHEMBL29769333 0.95 NPY4R (0.53) NPY4RNPY1RNPY2RNPY5RNOD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3187508-B1 LYSOSOMAL TARGETING PEPTIDES AND USES THEREOF BIOMARIN PHARM INC (US) 2026-04-22 EP disclosed
US-20230241187-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2023-08-03 US disclosed
US-20220354934-A1 Lysosomal Targeting Peptides and Uses Thereof BIOMARIN PHARMACEUTICAL INC. 2022-11-10 US disclosed
US-11351231-B2 Lysosomal targeting peptides and uses thereof BIOMARIN PHARMACEUTICAL INC. (US) 2022-06-07 US disclosed